Stereology

Importance of Stereological Analysis

Stereology is a statistical methodology for sampling and estimating the geometrical quantities of an object such as amount, length, profile area, surface area, and volume.

Stereology is now considered to be of paramount importance for the advancement of neuroscience and biomedical study. In fact, neuroscientists now recognize stereology as the preferred way to estimate numbers of cell populations in brain structures. Additionally, most highly regarded scientific journals now require or recommend that researchers use comprehensive stereological techniques for analyzing cell populations for publication.

The predominating hypothesis within the biomedical research community concludes that the application of clinical stereology propagates a more accurate assessment of scientific data (e.g., the number of surviving cells following drug therapy, etc) The precise evaluations of experiments such as these are of great importance in determining drug efficacy for course of treatment. Evidence supports the validity and importance of stereology in the advancement of pharmacology in conjunction with clinical trials of disease treatments. Therefore, we can expect to see applied utilization of clinical stereology as a means of assessing probability of regulatory approval as well as global market drug approval. The proper use of stereology in biological/pharmaceutical research can have major health and economic consequences.

MBF Labs’ expert technicians provide full stereological consultation and analysis of your experimental tissue specimens using the most advanced Stereology system, Stereo Investigator. MBF Labs can handle management of all types of studies, from small pilot studies to full-scale experimental analysis. A skilled scientist oversees all aspects of the analysis.